Supporting Embryo Development in ICSI Cycles
At Alpha IVF Singapore, centrifugation-free microfluidic sperm selection is available as part of our laboratory techniques used in ICSI treatments.
Unlike conventional sperm preparation methods that involve high-speed centrifugation, this approach allows sperm to be separated through a controlled microfluidic environment. This process may help reduce mechanical stress on sperm cells and supports the selection of motile and higher quality sperm to support better embryo quality.
Why Sperm Selection Matters in IVF
Sperm quality, including DNA integrity, is one of several factors that may influence:
- Fertilisation outcomes
- Blastocyst development
- Overall IVF treatment outcomes
Based on internal clinical data analysing over 9,600 oocytes in ICSI cycles involving PGT-A within the Alpha IVF Group, the use of centrifugation-free sperm preparation has been observed to be associated with:
- Higher blastocyst formation rates
- Higher euploid embryo rates
- Lower mosaic embryo rates
- Comparable fertilisation rates
In Alpha IVF Singapore, this centrifugation-free sperm preparation technique is applied as part of IVF treatment and may support blastocyst development as one of several contributing factors within a patient’s overall treatment.
Note: Individual outcomes may vary depending on factors such as age, underlying fertility conditions, and overall reproductive health.
Who May Benefit from This Approach
This laboratory technique may be considered in selected cases, including:
- Advanced maternal age
- Male factor infertility
- Recurrent implantation failure
Evidence-Based Laboratory Practice
At Alpha IVF Singapore, laboratory technologies are adopted following clinical evaluation and in line with prevailing clinical and laboratory standards in Singapore.
Our focus is to support embryo development within a carefully managed IVF process, alongside personalised care provided by our fertility specialists.
